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Human Papilloma Virus (HPV) DNA

icon Human Papilloma Virus (HPV) DNA

Infection in the cervix, vagina, vulva, urethra and in areas around the anus with Human papilloma viruses (HPVs), is one of the most common sexually transmitted diseases (STDs) of viral etiology worldwide.
Evidence from various fields: clinical, epidemiological, molecular and experimental, has established the relationship between some sexually transmitted HPV genotypes and cervical neoplasia throughout the world.
HPV genotypes are subdivided into High-risk, Intermediate-risk and Low-risk types. Detection of HPV DNA from cervical swabs, cervicovaginal lavages, from biopsies and formalin fixed paraffin embedded tissues, by PCR aids in identification of high risk genotypes with a sensitivity that is higher than tests such as immunocytochemistry, electron microscopy and Pap smear.
However, combined results of Pap smear and the HPV DNA test can help in determining the intervals for screening.

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